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Institute Associate Scientist II, In Vitro Pharmacology (Biochemistry)
Job Number:
38804930
Company Name:
MD Anderson Cancer Center
Job Location:
Houston, TX US
Job Categories:
Research Healthcare & Medical
Institute Associate Scientist II, In Vitro Pharmacology (Biochemistry)
Institute Associate Scientist II, In Vitro Pharmacology (Biochemistry) Job Category: Research Sub Category: Research Department: Applied Cancer Science Inst Salary: Employment Status: Full Time Work Week: Shift:
KEY FUNCTIONS
1. Under moderate supervision, conduct laboratory experiments and help establish and validate assays for both high-throughput screening to support target validation and lead optimization of drug discovery projects. 2. Execute routine weekly screening and counter screening assays for several drug discovery programs. 3. Execute standard in vitro screening protocols of novel therapeutic agents and troubleshoot issues. 4. Troubleshoot issues with assay performance, monitor assay quality and data release and capture. 5. Assist in the development and execution of additional biophysical and enzyme-based in vitro assays to characterize lead candidates. 6. Employ safe lab practices. 7. Maintain research records and laboratory notes. 8. Interact closely with other biologists and with medicinal chemists on discovery-based project teams
CORE COMPETENCIES
1. Self Motivation (Independent Contributor): Set high standards of performance; pursue goals with energy and persistence; drive for results and achievement. Use standards set by management. Take ownership for actions. Continually meet department goals. Demonstrate a personal sense of urgency in getting results. Use personal and management standards to complete assignments.
2. Technical/Functional Expertise (Independent Contributor): Demonstrate technical proficiency required to do the job; possess up-to-date knowledge in the profession; provide technical expertise to others. Apply basic technical/functional knowledge to complete work. Meet essential position requirements. Seek experiences and knowledge in technical/functional areas to gain additional expertise. Troubleshoot systems/processes effectively.
3. Analytical Thinking (Independent Contributor): Gather relevant information systematically; break down problems into simple components; make sound decisions. Recognize simple cause and effect relationships. Diagnose problems by breaking them down into simple tasks or activities. Identify relationships among a few parts of a problem. Scan own knowledge and experience base to determine potential solutions.
4. Team with Others (Independent Contributor): Encourage collaboration and input from all team members; value the contributions of all team members, and those beyond team; balance individual and team goals. Support and show respect to team members. Recognize how individual actions affect the team. Model team qualities, i.e. respect helpfulness and coping. Support team decisions once they are made and help to implement.
EDUCATION
Required: Bachelor's degree in Science or related field from an accredited university
Preferred: Bachelor's degree in biology, biochemistry, molecular biology, enzymology
Master's degree in a related field, such as biochemistry, enzymology or biology
EXPERIENCE
Required: With Bachelor's degree, two years of relevant research experience. With Master's degree, no experience is required.
Preferred: Hands-on laboratory experience in relevant industrial/academic lab. Strong knowledge in enzymology and biochemistry. The ideal candidate will have had previous experience with multiple enzyme families and assay formats.
Experience in using automated liquid handling and other automation would be beneficial.
Fluency with general biology lab procedures and familiarity with in-vitro biochemical/biophysical assay development for drug discovery.
Experience with spectroscopic techniques and safe handling of radioactive isotopes.
Candidates should have an interest in automation and in learning how to program and operate diverse automated compound screening platforms.
High attention to detail and ability to maintain clear records of experimental work is critical.
Demonstrated ability to work in team-oriented environment. Good verbal and written communication skills are essential.
WORKING CONDITIONS
Laboratory environment
This position requires: Working in Office Environment ____No __X_ Yes Working in Patient Care Unit (e.g. Nursing unit; outpatient clinic) _X_ No ____ Yes Exposure to human/animal blood, body fluids, or tissues ____No __X_ Yes Exposure to harmful chemicals ____No __X_ Yes Exposure to radiation ___ No __X_ Yes
